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<p>of damage to the endothelium is the release of pathological quantities of <a href="page.php?w=von_Willebrand_factor">von Willebrand factor</a>, which promote platelet aggregation and adhesion to the subendothelium, and thus the formation of potentially fatal thrombi.</p>

<p><a href="page.php?w=Angiosarcoma">Angiosarcoma</a> is cancer of the endothelium and is rare with only 300 cases per year in the US. However it generally has poor prognosis with a five-year survival rate of 35%.</p>

<p><big> Research </big></p>
<p><big> Cancer </big></p>
<p>It has been recognised</p><p>
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