from a hydrated substance through methods such as heating or drying up (desiccation). Dextrose monohydrate can be dehydrated to anhydrous dextrose in industrial setting. Dextrose monohydrate is composed of approximately 9.5% water by mass; through the process of dehydration, this water content is eliminated to yield anhydrous (dry) dextrose.

Anhydrous dextrose has the chemical formula , without any water molecule attached which is the same as glucose. Anhydrous dextrose on open air tends to absorb moisture and transform to the monohydrate,