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<p>occurs, the body sends signals to the inflammatory cells, <a href="page.php?w=Macrophage">macrophages</a>, which release IGF-1. IGF-1 is a hormone-insulin-like <a href="page.php?w=growth_factor">growth factor</a> which initiates the termination of damaged tissue. In some cases, this inflammatory response can be aggravated and cause increased swelling and <a href="page.php?w=edema">edema</a>, which can prolong the recovery process.It is hypothesized that the practice originated from James Arnott(1797-1883), a senior physician of Brighton Infirmary,</p><p>
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