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<p>the terminal stages of acute <a href="page.php?w=head_injury">head injury</a> and may indicate imminent <a href="page.php?w=brain_herniation">brain herniation</a>. It can also be seen after the intravenous administration of <a href="page.php?w=epinephrine">epinephrine</a> and similar drugs. It was first described in detail by American <a href="page.php?w=neurosurgery">neurosurgeon</a> <a href="page.php?w=Harvey_Cushing">Harvey Cushing</a> in 1901.</p>

<p><big> Definition </big></p>
<p>The Cushing reflex classically presents as an increase in <a href="page.php?w=systole_%28medicine%29">systolic</a></p><p>
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