the G_i/o (G_i/G_o) family or G_i/o/z/t family to include closely related family members. G alpha subunits may be referred to as G_i alpha, G_?i, or G_i?.

The G_i/o/z/t family is one of the four families of G protein alpha subunits, which are a core component of G-protein-coupled receptor signaling: one of the largest families of cell receptors. In particular, G_i/o/z/t proteins