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<p>Hy's Law cases have three components:<br/>
* The drug causes hepatocellular injury, generally defined as an <a href="page.php?w=Alanine_transaminase">ALT</a> or <a href="page.php?w=Aspartate_transaminase">AST</a> elevated 3-fold or more above the upper limit of normal, often with <a href="page.php?w=aminotransferase">aminotransferase</a>s much greater (5-10x) than the upper limit of normal.<br/>
* Among subjects showing such aminotransferase elevations, they also have elevation of their serum total bilirubin of greater than 2× the upper limit</p><p>
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