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<p>The DNA double-strand break <a href="page.php?w=DNA_end">ends</a> and is required for the <a href="page.php?w=non-homologous_end_joining">non-homologous end joining</a> (NHEJ) of the <a href="page.php?w=DNA_repair">DNA repair</a> pathway.  It is also required for <a href="page.php?w=V%28D%29J_recombination">V(D)J recombination</a>, which utilizes the NHEJ pathway to promote antigen diversity in the mammalian <a href="page.php?w=immune_system">immune system</a>. Ku70 is key for sensing and responding to cytosolic DNA, which is essential for the</p><p>
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