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<p><a href="page.php?w=Sinaloa">Sinaloa</a>, <a href="page.php?w=Mexico">Mexico</a>, in the 1970s, by the drug trafficker <a href="page.php?w=Rafael_Caro_Quintero">Rafael Caro Quintero</a> and consists of separating male plants as soon as they are known to be male, in order to avoid <a href="page.php?w=pollination">pollination</a> of female <a href="page.php?w=pistils">pistils</a>. The seeds are not useful for recreational purposes and require the plant to make a great expenditure of energy that could be invested in increasing the <a href="page.php?w=tetrahydrocannabinol">tetrahydrocannabinol</a></p><p>
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