Nevada, but all organizations based in the Las Vegas area, such as the Southern Nevada Health District, effectively limit the term to the Las Vegas Valley.

Geographically, parts of Southern Nevada are within the Mojave Desert. The population of the region, as measured by the 2020 U.S. Census, is 2,327,680, with 2,265,461 living in the Las Vegas Valley (i.e., Clark County). Over time and influenced by climate change,