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during an alternate history of post-World War II United States, the series follows humans who contracted the Wild Card virus, an alien virus that rewrites DNA and mutates survivors. Those who acquire crippling and/or repulsive physical conditions are known as Jokers, while those who acquire superhuman abilities are known as Aces, and those few who acquire minor, insignificant powers not worthy of being called aces are known as Deuces.

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