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(CoASH or CoA) consists of a ?-mercaptoethylamine group linked to pantothenic acid (vitamin B5) through an amide linkage and 3'-phosphorylated ADP. The acetyl group (indicated in blue in the structural diagram on the right) of acetyl-CoA is linked to the sulfhydryl substituent of the ?-mercaptoethylamine group. This thioester linkage is a "high energy" bond,

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