desert. Vegetation has little or no effect on the distribution of canyon mice, it is instead associated with rocky substrate than any plant. Canyon mice forage in areas with shrub-like vegetation which can be used for protection against predators. It is the only species in the Peromyscus crinitus species group.

Canyon mice eat seeds, green vegetation, and insects. Small animals and insects make up a larger portion of diet when seeds and vegetation are rare. They breed in the spring and summer. Females