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or swelling around the eye on the affected side. Cluster headaches are unique in their periodicity and regularity: the headaches occur at around the same hour every day during a cluster period, which typically lasts 8-10 weeks a year. Between cluster periods are pain-free intervals without headaches, which last a little less than one year, but some patients can have chronic cluster headaches without remission periods. The disease is considered among the most painful conditions known to medical science.

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