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<p>or <a href="page.php?w=Irritation">irritants</a> (<a href="page.php?w=irritant_contact_dermatitis">irritant contact dermatitis</a>). Allergic contact dermatitis involves a delayed type of hypersensitivity and previous exposure to an allergen to produce a reaction. Irritant contact dermatitis is the most common type and represents 80% of all cases. It is caused by prolonged exposure to irritants, leading to direct injury of the <a href="page.php?w=Epidermis">epidermal cell</a>s of the skin, which activates an <a href="page.php?w=immune_response">immune response</a>,</p><p>
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