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<p>and wines. </p>

<p>With the advent of <a href="page.php?w=ultra-processed_foods">ultra-processed foods</a> in the late 20th century, many additives having both natural and artificial origin were introduced. Food additives also include substances that may be introduced to food indirectly (called "indirect additives") in the manufacturing process through <a href="page.php?w=food_packaging">packaging</a>, storage or transport.</p>

<p>In Europe and internationally, many additives are designated with <a href="page.php?w=E_number">E number</a>s,</p><p>
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