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<p>cycle, and is the enzyme responsible for linking the cycle to one-carbon metabolism via the <a href="page.php?w=folate">folate</a> cycle. There are two primary forms of this enzyme, the <a href="page.php?w=Vitamin_B12">Vitamin B<sub>12</sub></a> (cobalamin)-dependent (MetH) and independent (MetE) forms, although minimal core methionine synthases that do not fit cleanly into either category have also been described in some <a href="page.php?w=Anaerobic_organism">anaerobic bacteria</a>. The two dominant forms of the enzymes appear to be evolutionary</p><p>
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