then lost the city to their successors in the Indo-Greek Kingdom around the mid-2nd century BC. Buddhism was greatly patronized by these rulers, and the majority of the city's population was adherents of the religion. Indo-Scythians expelled the Indo-Greeks by the mid 1st century BC, but lost the city to the Kushan Empire about 100 years later.

It is mentioned as Kophes or Kophene in some classical Greek writings.