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<p>childhood and adolescence. Experience can expand or contract cortical zones devoted to particular movements, and recovery after injury may recruit premotor and somatosensory contributions to descending pathways.</p>

<p><big> Maturation of corticospinal systems </big></p>
<p>Transient bilateral projections are common in infancy; progressive myelination, synaptic pruning and strengthening of cortico-motoneuronal connections accompany the emergence of fine manual dexterity. Diffusion MRI and TMS demonstrate increasing tract integrity and decreasing motor</p><p>
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