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<p>the chromosome and a loss of genetic information due to the fusion of two chromosome pieces with a centromere. This results in a singular chromosome having two centromeres, due to the fusion of two chromosomal pieces with one centromere each, therefore resulting in the fusion of two centromeres.</p>

<p>Ring chromosomes are chromosomes that form when the ends of the previous chromosomes break off to form a circular structure. This results in a loss of genetic material as well as the potential loss of the chromosomal centromere.</p>

<p><big>DNA double-strand breaks with translocations</big></p><p>
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