Lane again built fortifications to protect his men as they brought the salt aboard. Grenville's ships then sailed to La Isabela, where the Spanish set aside hostilities to trade with the well-armed English fleet. On June 7, Grenville left Hispaniola to continue to the Outer Banks.

The fleet sailed through an inlet at Wococon Island (near present-day Ocracoke Inlet) on June 26. Tiger struck a shoal,