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may be years or even a decade or more away.

Induced pluripotent stem cells obtained reprogramming patients' cells, for example leukocytes, are a promising tool to study these pathologies and develop personalized therapies.

History

X-linked agammaglobulinemia was one of the first described primary immunodeficiencies, discovered by Ogden Bruton in 1952. Primary immunodeficiencies were initially classified in 1970 by a committee

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