Antoine Étienne Reynaud Augustin Serres and Jean Louis Armand de Quatrefages de Bréau, and by the late 1850s it became his lifetime interest. Broca defined Anthropology as "the study of the human group, considered as whole." Like other scientists, he rejected relying on religious texts, and looked for a scientific explanation of human origins.

In 1857, Broca was presented with a hybrid leporid,