system of fruit flies. However, applications to larger tissue blocks of entire nervous systems have traditionally had difficulty with projections that span longer distances.

In March 2011, the journal Nature published a pair of articles on micro-connectomes: Bock et al. and Briggman et al. In both articles, the authors first characterized the functional properties of a small subset of cells, and then manually traced a subset of the processes emanating from those cells to obtain a partial