in cells.

Disease involvement

Despite a high degree of sequence similarity, RhoGDI1 and RhoGDI2 are very different in their binding affinities for specific GTPases, and more importantly, in their roles in tumor formation and spread of tumor to other organs (the process of metastasis). For example, RhoGDI2 functions as a suppressor of metastasis but not a tumor suppressor in bladder cancer

1.Previous
3.Next