1.Previous
3.Next

measures of potency, such as EC₅₀ for excitatory drugs. EC₅₀ represents the dose or plasma concentration required for obtaining 50% of a maximum effect in vivo.

IC₅₀ can be determined with functional assays or with competition binding assays.

Sometimes, IC₅₀ values are converted to the pIC₅₀ scale.

:

Due to the minus sign,

1.Previous
3.Next