survived her husband Robert who died in 1232. She did not remarry and she herself died in 1251. She was buried at Sawtry Abbey, alongside her husband and her father.

Issue

Isobel and her husband Robert de Brus had at least 2 sons and a daughter:
* Robert de Brus, who became the 5th Lord of Annandale and married Isabel de Clare, daughter of Gilbert de Clare Earl of Hertford and Gloucester; had issue.
* Bernard de Brus of Exton,

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