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domain, and a WD40 domain. Possible cellular functions of LRRK2 include the cytoskeleton, membrane trafficking, iron homoeostasis and mitochondrial function.

LRRK2 interacts with the C-terminal R2 RING finger domain of parkin, and parkin interacted with the COR domain of LRRK2. Expression of mutant LRRK2 induced apoptotic

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