in 1894 in the sap of the Japanese lacquer tree, where it helps to form lacquer, hence the name laccase.

Active site

thumbThe active site consists of four copper centers, which adopt structures classified as type I, type II, and type III. A tricopper ensemble contains types II and III copper (see figure). It is this center that binds O₂ and reduces it to water. Each Cu(I,II) couple delivers

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