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and pethidine (meperidine). The harmful effects of MPTP were first discovered when a group of people fell ill after injecting illegally obtained MPPP.

Toxicity

Injection of MPTP causes rapid onset of Parkinsonism, hence users of MPPP contaminated with MPTP will develop these symptoms.

MPTP itself is not toxic, but it is a lipophilic compound and can therefore cross the blood-brain barrier.

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