that the amoeboflagellate contains actin and microtubule cytoskeletons, mitotic and meiotic machinery, and several transcription factors. Naegleria's mitochondrial genome encodes some components of a mitochondrial c and c1 maturation system.

Naegleria's mitochondria resemble the evolutionary intermediate thought to have occurred within the ancestor of all eukaryotes, because of its presence of mitochondrial Fe-hydrogenase and complete aerobic respiration system. The Naegleria genome is able to oxidize