which ended with defeat and burning of Poltava by the hetman's forces. In 1664 the regiment was attacked by troops of Right-bank hetman Pavlo Teteria. In 1666 the regiment rebelled against Left-bank hetman Ivan Briukhovetsky.

During the 18th century Poltava regiment functioned as one of 10 administrative subdivisions of the Hetmanate. In 1775, the regiment was officially