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<p>to involve a combination of genetic and environmental factors. The underlying mechanism involves the body's <a href="page.php?w=immune_system">immune system</a> attacking the joints. This results in inflammation and thickening of the <a href="page.php?w=synovium">joint capsule</a>. It also affects the underlying <a href="page.php?w=bone">bone</a> and <a href="page.php?w=cartilage">cartilage</a>. The diagnosis is mostly based on a person's signs and symptoms. <a href="page.php?w=medical_imaging">X-rays</a> and laboratory testing may support a</p><p>
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