is overlap, anti-TPO antibodies are most commonly associated with Hashimoto's thyroiditis and activating TRAb's are most commonly associated with Graves' disease. Thyroid microsomal antibodies were a group of anti-thyroid antibodies; they were renamed after the identification of their target antigen (TPO).

Subtypes

Anti-thyroid antibodies can be subdivided into groups according to their target antigen.

Anti-TPO antibodies

Anti-thyroid peroxidase (anti-TPO) antibodies are specific for the autoantigen

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