impaired, large numbers of Mycobacterium leprae appear in the macrophages and the infected patients develop papules at the entry site, marked by a folding of the skin. Gradual destruction of cutaneous nerves lead to what is referred to as "classic lion face". Extensive penetration by this bacterium may lead to severe body damage; for example the loss of bones, fingers, and toes.

Symptoms of a Mycobacterium leprae infection

The symptoms of a Mycobacterium leprae infection, also known as

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