evolutionarily conserved domains. BCL6 contains a (1) N-terminal BTB/POZ domain (Broad-complex, Tramtrack and Brick-a-brac/Pox virus and Zinc finger family domain), (2) a central RN2 region, and (3) another zinc finger at the C-terminal end. This structure is vital to BCL6's function - an exon 7 skipping splice variant encodes a shorter form of the protein which lacks the first two zinc fingers