point to the role of hedgehog signaling in regulating adult stem cells involved in maintenance and regeneration of adult tissues. The pathway has also been implicated in the development of some cancers. Drugs that specifically target hedgehog signaling to fight diseases are being actively developed by a number of pharmaceutical companies.

Introduction

Signaling cascades

Cells require a full and functional cellular machinery to live. When they belong to complex multicellular organisms, they need to communicate among

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