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<p>in 1976-1977.</p>

<p><big> Method </big></p>
<p>Laboratory animals (<a href="page.php?w=mammal">mammal</a>s, e.g. mice) are first exposed to the antigen against which an antibody is to be generated. Usually this is done by a series of injections of the antigen in question, over the course of several weeks. These injections are typically followed by the use of in vivo <a href="page.php?w=electroporation">electroporation</a>, which significantly enhances the immune response. Once <a href="page.php?w=splenocyte">splenocyte</a>s are isolated from the mammal's</p><p>
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