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phospholipase C?2 (PLC?2), and phosphatidyl inositol-3 kinase. These kinases generate activation signals critical for proliferation, Ca²⁺ mobilization, and cell differentiation.

Lyn also plays an essential role in transmitting inhibitory signals by phosphorylating tyrosine residues within the immunoreceptor tyrosine-based inhibitory motifs (ITIMs) of regulatory proteins such

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