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<p>and migrating through the periphery, where they differentiate into varied cell types. The emergence of the neural crest was important in <a href="page.php?w=vertebrate">vertebrate</a> evolution because many of its structural derivatives are defining features of the vertebrate <a href="page.php?w=clade">clade</a>.  Underlying the development of the neural crest is a <a href="page.php?w=gene_regulatory_network">gene regulatory network</a>, described as a set of interacting signals, <a href="page.php?w=transcription_factors">transcription factors</a>,</p><p>
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