in reductive (and usually anabolic) reactions.

Biosynthesis

NADP

In general, NADP⁺ is synthesized before NADPH is. Such a reaction usually starts with NAD⁺ from either the de-novo or the salvage pathway, with NAD⁺ kinase adding the extra phosphate group. ADP-ribosyl cyclase allows for synthesis from nicotinamide in the salvage pathway,

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