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impact of these compounds has increased since the 1990s. These surfactants have a mild to medium estrogenic function. Consequently, this class of detergents has been effectively restricted for commercial "down-the-drain" applications in Europe, and these compounds are no longer used by U.S. laundry manufacturers. On January 14, 2016, the European Commission amended existing restriction on NPEs under the Registration, Evaluation, Authorisation and Restriction of Chemicals

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