indicate a 6- to 11-day cycle of enamel formation.

Causes

Occasional darker striae or grooves of Retzius result from systemic disturbances in the human body. For example, a fever can cause some lines to appear darker than those surrounding them. Normally, amelogenesis involves a period of enamel matrix formation and a rest period. In case of any disturbance, the rest periods are prolonged and occur close to one another. Consequently, the line of Retzius appears

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