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<p>the 1990s. The <a href="page.php?w=five-year_survival_rate">five-year survival rate</a> in the United States is 71%.</p>

<p><big>Signs and symptoms</big></p>
<p>Symptoms of anal cancer can include pain or pressure in the anus or rectum, a change in bowel habits, a lump near the anus, rectal bleeding, itching or discharge. Bleeding may be severe.</p>

<p><big>Risk factors</big></p>
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* <a href="page.php?w=Human_papillomavirus">Human papillomavirus</a>: Examination of squamous cell carcinoma tumor tissues from patients in Denmark and Sweden showed a high proportion</p><p>
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