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<p>are some limitations:  <a href="page.php?w=confounding_variable">confounding factors</a>, geographic coverage, annular resolution, and collection difficulties.  The field has developed various methods to partially adjust for these challenges.</p>

<p><big>Confounding factors</big></p>
<p>There are multiple climate and non-climate factors as well as <a href="page.php?w=nonlinearity">nonlinear</a> effects that impact tree ring width.  Methods to isolate single factors (of interest) include botanical studies to calibrate growth influences and sampling of</p><p>
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