slightly stronger than morphine as an analgesic with a similar side effect profile. The relative potency of dihydromorphine is about 1.2 times that of morphine. In comparison, the relative potency of dihydrocodeine is around 1.2 to 1.75 times that of codeine.

Pharmacology

Dihydromorphine acts as an agonist at the u-opioid with a K_i value of 2.5 nM compared to 4.9 nM of morphine,

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