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<p><big>Extracellular matrix</big></p>
<p>The extracellular matrix of granulation tissue is created and modified by <a href="page.php?w=fibroblasts">fibroblasts</a>.  Initially, it consists of a network of <a href="page.php?w=type-III_collagen">type-III collagen</a>, a weaker form of the structural protein that can be produced rapidly.  This is later replaced by the stronger, long-stranded <a href="page.php?w=type-I_collagen">type-I collagen</a>, as evidenced in <a href="page.php?w=scar">scar</a> tissue.</p>

<p><big>Immunity</big></p>
<p>The main immune cells active</p><p>
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