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DNA) with full LTRs. The LTRs then mediate integration of the DNA via an LTR specific integrase into another region of the host chromosome.

Retroviruses such as human immunodeficiency virus (HIV) use this basic mechanism.

Dating retroviral insertions

As 5' and 3' LTRs are identical upon insertion, the difference between paired LTRs can be used to estimate the age of ancient retroviral insertions. This method of dating

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