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and in front of the septum. The BNST, hypothalamic nuclei, and septal nuclei are all in close proximity with each other and share many projections. It correlates with anxiety in response to threat monitoring. It is thought to act as a relay site within the hypothalamic-pituitary-adrenal axis and regulate its activity in response to acute stress. However, the stress response is time-related and the BNST does not activate for contextual fear.

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