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has been shown to interact with at least six other Atg proteins, namely Atg 29, 31, 11, 20 and 24. Of all these, Atg13 has been shown to have roles in both autophagy and Cvt functions; Atg17, 29 and 31 have only functions in autophagy, while Atg11, 20 and 24 only take part in the Cvt pathway. Based on yeast two-hybrid data and affinity isolation, Atg1 is found to be in a complex with Atg13 and Atg17. The observation that Atg17 interacts with Atg13 in the absence of Atg1 but not vice versa suggests that

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