degranulation, phagocytosis, and oxidative burst, which allows neutrophils to clear opsonized pathogens.

Mechanism and regulation

These receptors bind to the Fc portion of IgG antibodies, which then activates antibody-dependent cell-mediated cytotoxicity (ADCC) in human NK cells. CD16 is required for ADCC processes carried out by human monocytes. In humans, monocytes expressing

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